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Colorectal Cancer Updates 2013

5 reasons to stop avoiding that colonoscopy

Monday, December 23, 2013

Colonoscopy is highly effective at preventing colorectal cancer, the second-deadliest type of cancer, because it allows a doctor to detect precancerous growths in the colon and remove them on the spot.

Yet only about half of Americans age 50 and older get any kind of screening for colorectal cancer, colonoscopy or otherwise, according to Otis Brawley, chief medical officer of the American Cancer Society. He estimates that an additional 15,000 to 20,000 lives could be saved each year if that rate rose to 90 or 95 percent.

Study shows colonoscopy better than sigmoidoscopy in protecting against colorectal cancer

Friday, November 22, 2013

A study in the New England Journal of Medicine finds that colonoscopy appears to reduce the risk of developing or dying from colorectal cancer more powerfully than does sigmoidoscopy, a similar procedure that examines only a portion of the colon. The investigation, which analyzes data from two long-term studies, also identifies molecular features that may help explain tumors that are diagnosed despite an individual’s having recently undergone colonoscopy.

Study finds key link responsible for colon cancer initiation and metastasis

Monday, November 11, 2013

Chronic inflammation has long been known as a key risk factor for cancer – particularly colon cancer – but the exact mechanisms of how inflammation heightens the immune response, and ultimately influences the initiation and progression of cancer have remained elusive. It is well established that anti-inflammatory drugs, like aspirin, reduce the risk of colorectal cancer.

Now, an ASU research team led by Biodesign Institute executive director Ray DuBois has shown that a key genetic culprit, called CXCR2, is implicated in the tumor formation, growth and progression in a mouse model of colon cancer.

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